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Lie-Ding Shiau


Lie-Ding Shiau


Tel:+886-3-2118800 ext. 5291



Work Experience
Department of Chemical and Materials Engineering, Chang Gung University
Department of Chemical and Biomolecular Engineering, Rice University, USA
visiting professor

Department of Chemical and Materials Engineering, Chang Gung University 

professor and chairperson
Department of Chemical and Materials Engineering, Chang Gung University
associate professor
Development center for biotechnology, Taiwan
associate researcher
Department of Chemical and Biochemical Engineering, Rutgers University, USA 
post-doctoral researcher
Academic Education
Chemical Engineering, Michigan State University, USA
Chemical Engineering, National Taiwan University

Crystallization fundamentals and applications

Crystallization growth and nucleation kinetics, mixing behavior and crystallizer design

Distillative freezing

Developing an innovative energy-saving separation technique, called distillative freezing (DF), to separate mixtures of volatile compounds. The major features of this new separation technique are: (1) production of superpure chemicals exceeding 99.9%, (2) reduction of energy consumption, (3) reduction of capital costs of the equipment, (4) accomplishment of pollution prevention.

Modeling of polymerization and biomedical reactions

Application of statistical methods in modeling the immune-complex formation process, application of statistical methods in modeling of the size distribution of the polymerization process


Recent Publications

  1. Shiau, L. D., 1995, "An extended study on the average molecular weights of nonlinear polymers", Macromolecules, 28, p.6273-6277. (SCI, EI)

  2. Shiau, L. D., 1996, "A systematic analysis of average molecular weights and gelation conditions for branched immune complexes: The interaction between a multivalent antigen with distinct epitopes and many different types of bivalent antibodies", Biopolymers, 39, p.445-454. (SCI, EI)

  3. Shiau, L. D., 1996, "A probability model on the average properties for the further stepwise polymerization of prepolymers ", Macromolecular Theory and Simulations, 5, p.1195-1205. (SCI)

  4. Shiau, L. D., 1998, "Average properties of the resulting polymer blends formed between two polydisperse reactive polymers", Polymer, 39, p.1317-1326. (SCI, EI)

  5. Shiau, L. D., 1999, "A comparative study of the branched polymers formed by T-shaped junctions and by H-shaped junctions”, Macromolecular Theory and Simulations, 8, p586-593. (SCI)

  6. Shiau, L. D.; Cheng, S. H.; Liu, Y. C., 1999, "Modelling of a fluidized bed crystallizer-operated in a batch mode", Chem. Eng. Sci., 54, p.865-871. (SCI, EI)

  7. Shiau, L. D.; Ling, T. R.; Tseng, D. S., 2000, "Consecutive esterification of 1,4-Butanediol with acrylic acid by homogeneous catalysis ”, Chem. Eng. Comm., 179, p133~148. (SCI, EI)

  8. Shiau, L. D., 2001, "The average properties of block copolymers formed via the one-prepolymer method and the two-prepolymer method”, Macromolecular Theory and Simulations, 10, p.179-186. (SCI)

  9. Shiau, L. D.; Lu, T.S., 2001, “Interactive effects of particle mixing and segregation on the performance characteristics of a fluidized bed crystallizer”, Ind. Eng. Chem. Res., 40, p.707-713. (SCI, EI)

  10. Shiau, L. D., 2002, "Molecular weight distribution of step-growth comb-branched polymers”, Polymer, 43, p2835-2843. (SCI, EI)

  11. Shiau, L. D., 2003, "The distribution of the dislocation activities among crystals in sucrose crystallization", Chem. Eng. Sci., 58, p5299-5304 (SCI, EI)

  12. Shiau, L. D., 2004, "A probability model of star-branched polymers formed by connecting polydispersed primary chains onto a multifuntional coupling agent", Macromolecular Theory and Simulations, 13, p.783-789. (SCI)

  13. Shiau, L. D.; Lu, T. S., 2004, "Programmed cooling of a batch crystallizer in the presence of growth rate dispersion", J. Chin. Inst. Chem. Engrs., 35(6), p.285-290. (SCI, EI)

  14. Shiau, L. D., Wen, C. C.; Lin B. S., 2005, "Separation and purfication of p-xylene from the mixture of m-xylene and p-xylene by distillative freezing", Ind. Eng. Chem. Res., 44(7), p.2258-2265 (SCI, EI) 

  15. Shiau, L. D.; Wen, C. C.; Lin, B. S., 2006, “Application of distillative freezing in the separation of o-xylene and p-xylene”, AIChE J., 52(5), p.1962-1967. (SCI, EI)

  16. Shiau, L. D.; Lu, T. S., 2006, “Modeling the nonideal mixing behavior in a continuous-stirred crystallizer”, Computers & Chemical Engineering, 30, p.970-977. (SCI, EI)

  17. Shiau, L. D. ; Liu, K. F. ; Jang, S. M. ; Wu, S. C., 2008, "Separation of diethylbenzene isomers by distillative freezing”, J. Chin. Inst. Chem. Engrs., 39, p. 59-65.(SCI, EI)

  18. Shiau, L. D.; Wen, C. C.; Lin, B. S., 2008, “Separation of p-xylene from the multicomponent xylene system by stripping crystallization”, AIChE J., 54(1), p.337-342. (SCI, EI)

  19. Shiau, L. D.; Lu, Y. F.; 2009, “Modeling solute clustering in the diffusion layer around a growing crystal”, J. Chem. Phys., 130, p.094015 (1-7). (SCI, EI)

  20. Shiau, L. D.; Yu, C. C.; 2009, “Separation of the benzene/cyclohexane mixture by stripping crystallization”, Sep. Purif. Technol., 66, p.422-426. (SCI, EI)